Document Detail

Familial muscle cramps with autosomal dominant transmission.
MedLine Citation:
PMID:  7389765     Owner:  NLM     Status:  MEDLINE    
A family is described with generalized muscle cramps inherited as an autosomal dominant trait and with maximal expression during adolescence. The age of onset varies between 10 and 15 years. Muscle enzymes are elevated with a peak level between 15 and 25 years. The complaints seem to disappear after the age of 25 years. EMG and muscle biopsies suggest a neurogenic origin of the cramps.
P Van den Bergh; J A Bulcke; R Dom
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European neurology     Volume:  19     ISSN:  0014-3022     ISO Abbreviation:  Eur. Neurol.     Publication Date:  1980  
Date Detail:
Created Date:  1980-09-23     Completed Date:  1980-09-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  207-12     Citation Subset:  IM    
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MeSH Terms
Genes, Dominant
Middle Aged
Muscle Cramp / enzymology,  genetics*,  pathology
Muscles / enzymology,  pathology

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