Document Detail

Familial mitral valve prolapse and myotonic dystrophy.
MedLine Citation:
PMID:  937918     Owner:  NLM     Status:  MEDLINE    
When a patient with mitral valve prolapse was found to have myotonic dystrophy, his family was studied to ascertain the occurrence of these abnormalities. Of 25 relatives screened, 8 had evidence of both myotonic dystrophy and mitral valve prolapse and 2 had evidence of myotonic dystrophy alone. Thirteen patients had evidence of neither condition and 1 had mitral valve prolapse alone. The association of these two conditions within a family has not previously been observed and valvular heart disease has not been recognized in myotonic dystrophy. This association should be looked for in other patients.
S J Winters; B Schreiner; R C Griggs; P Rowley; N C Nanda
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of internal medicine     Volume:  85     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-08-23     Completed Date:  1976-08-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  19-22     Citation Subset:  AIM; IM    
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MeSH Terms
Cardiomyopathies / complications,  genetics*
Middle Aged
Mitral Valve Insufficiency / etiology,  genetics*
Myotonic Dystrophy / complications*,  genetics

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