Document Detail

Familial microscopic hematuria caused by hypercalciuria and hyperuricosuria.
MedLine Citation:
PMID:  10620556     Owner:  NLM     Status:  MEDLINE    
We report 12 patients belonging to five different families in whom persistent isolated microhematuria was associated with hypercalciuria and/or hyperuricosuria. Four patients had episodes of gross hematuria, three patients had passed renal stones, and a history of nephrolithiasis was obtained in four of the families (80%). Calcium oxalate and uric acid crystals were commonly observed in the urine sediments. Urinary erythrocytes had a normal appearance on phase-microscopic examination. Reduction of calciuria and uricosuria by thiazide diuretics, allopurinol, forced fluid intake, and dietetic measures led to a persistent normalization of urine sediment with complete disappearance of hematuria. Determination of calcium and uric acid urinary excretions should be included in the study of familial hematuria.
M Praga; R Alegre; E Hernández; E Morales; B Domínguez-Gil; A Carreño; A Andrés
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  35     ISSN:  1523-6838     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-01-12     Completed Date:  2000-01-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  141-5     Citation Subset:  IM    
Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain.
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MeSH Terms
Calcium / urine*
Hematuria / diagnosis,  genetics*,  urine
Kidney Function Tests
Middle Aged
Uric Acid / urine*
Reg. No./Substance:
69-93-2/Uric Acid; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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