Document Detail

Familial intracranial ependymomas. Report of three cases in a family and review of the literature.
MedLine Citation:
PMID:  16459998     Owner:  NLM     Status:  MEDLINE    
Familial cases of intracranial ependymomas have been well documented in the literature. The authors present two cases from a family in which three members harbored intracranial ependymomas. A 54-year-old man with fourth ventricular ependymoma underwent resection of the tumor followed by radiation therapy. His son presented at age 36 years with a fourth ventricular tanycytic ependymoma and underwent total resection of the ependymoma with postoperative radiation therapy. The father's sister had been treated at another institution for a posterior fossa ependymoma.The association of ependymomas with molecular genetic alterations in chromosome 22 has been previously described. Further investigation of the genetic influences may lead to better therapeutic approaches for this relatively rare clinicopathological entity.
Vassilios G Dimopoulos; Kostas N Fountas; Joe Sam Robinson
Related Documents :
24961548 - Gastrinoma and neurofibromatosis type 2: the first case report and review of the litera...
2171328 - Familial case of may-hegglin anomaly associated with familial spastic paraplegia.
3906608 - Aplasia cutis congenita: a report of 12 new families and review of the literature.
2107218 - Genetic counseling in segmental neurofibromatosis.
12714548 - Outbreak of poliomyelitis due to type 3 poliovirus, northern india, 1999-2000: injectio...
6129588 - Preoperative evaluation of hemodynamic factors in cerebral arteriovenous malformations ...
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2006-01-15
Journal Detail:
Title:  Neurosurgical focus     Volume:  20     ISSN:  1092-0684     ISO Abbreviation:  Neurosurg Focus     Publication Date:  2006  
Date Detail:
Created Date:  2006-02-07     Completed Date:  2006-05-02     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  100896471     Medline TA:  Neurosurg Focus     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E8     Citation Subset:  IM    
Department of Neurosurgery, Medical Center of Central Georgia, Mercer University, School of Medicine, Macon, Georgia, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cerebral Ventricle Neoplasms / diagnosis,  surgery*
Ependymoma / diagnosis,  surgery*
Family Health*
Magnetic Resonance Imaging / methods
Middle Aged
Radiotherapy / methods*
Review Literature as Topic
Spinal Cord Neoplasms / diagnosis,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Focal cortical dysplasia: a review of pathological features, genetics, and surgical outcome.
Next Document:  A novel minimally invasive presacral approach and instrumentation technique for anterior L5-S1 inter...