Document Detail

Familial idiopathic pulmonary fibrosis in three Lebanese siblings. Case report with long-term follow-up.
MedLine Citation:
PMID:  17044635     Owner:  NLM     Status:  MEDLINE    
This is the first report of a familial cluster of idiopathic pulmonary fibrosis (IPF) in Lebanon. This rare variant of IPF has an autosomal dominant mode of inheritance with variable expressivity, and is commonly associated with a mutation of the surfactant protein C gene. The patients are younger at diagnosis but have otherwise identical clinical, radiological, and histological features as the more common non-familial cases. IPF is an invariably fatal disease with no effective treatment. Lung transplantation remains the only chance for more prolonged survival and must be considered in young patients.
Nadim Kanj; Mouhamad Abdallah; Ayman Tawil
Related Documents :
17134655 - Immunology and pathology of intestinal trematodes in their definitive hosts.
603745 - Inheritance of porphyria cutanea tarda. analysis of 14 cases in 5 families.
3828965 - Familial pancreatic adenocarcinoma in three generations. a case report and a review of ...
24720145 - Adenocarcinoma arising in gastric heterotopic pancreas. case report and review of the l...
20084575 - Benign fibroblastic polyp of the colon: a case report.
10923855 - Gonorrhea--united states, 1998.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Le Journal médical libanais. The Lebanese medical journal     Volume:  54     ISSN:  0023-9852     ISO Abbreviation:  J Med Liban     Publication Date:    2006 Jan-Mar
Date Detail:
Created Date:  2006-10-18     Completed Date:  2007-11-06     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  0375352     Medline TA:  J Med Liban     Country:  Lebanon    
Other Details:
Languages:  eng     Pagination:  45-9     Citation Subset:  IM    
Department of Internal Medicine, American University of Beirut, Lebanon.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Family Health
Pulmonary Fibrosis* / diagnosis,  genetics,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Subcutaneous nodular sarcoidosis and systemic involvement successfully treated with doxycycline.
Next Document:  Mycotic aneurysm of the tibioperoneal trunk. An extremely rare localization with pseudo-phlebitis cl...