Document Detail

Familial haemophagocytic reticulosis. Report of 2 cases in sibs.
MedLine Citation:
PMID:  1154199     Owner:  NLM     Status:  MEDLINE    
Two cases of familial haemophagocytic reticulosis occurring in sibs are described. The disease is characterised by a widespread proliferation of histocytes showing haemophagocytosis and it usually manifests clinically with haematological abnormalities. The initial presentation may be that of a meningo-encephalitic illness, the result of a lymphohistiocytic infiltration of the meninges and cerebral tissues. The clinical course and pathological features are described and the differential diagnosis is discussed.
J B Botha; L B Kahn; R O Kaschula
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  49     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1975 Jul 
Date Detail:
Created Date:  1975-10-30     Completed Date:  1975-10-30     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  1305-8     Citation Subset:  IM    
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MeSH Terms
Bone Marrow / pathology
Brain / pathology
Child, Preschool
Diagnosis, Differential
Histiocytosis, Langerhans-Cell / diagnosis
Lymph Nodes / pathology
Lymphatic Diseases / diagnosis,  genetics*,  pathology
Meninges / pathology
Spleen / pathology

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