Document Detail

Familial florid cemento-osseous dysplasia--a case report and review of the literature.
MedLine Citation:
PMID:  9462035     Owner:  NLM     Status:  MEDLINE    
Cemento-osseous dysplasia is a fairly common lesion of the jaws originating from the elements of the periodontal ligament. Most lesions do not have a hereditary basis, however a few familial cases have been documented. This is the first report of the florid form of cemento-osseous dysplasia in an African family. The mother, son and one daughter exhibited multiple sclerotic cemental masses of the jaws with large tumour-like swellings in the symphyseal area of the mandible. In the case of the mother the lesions had become infected. The familial form of cemento-osseous dysplasia differs from the non-hereditary type in that the lesions present in children, all cases are florid in nature, there is no predilection for black females, the rate of growth appears to be more rapid and the symphyseal area of the mandible is most severely affected. The mode of transmission appears to be autosomal dominant with variable phenotypic expression.
H Coleman; M Altini; J Kieser; M Nissenbaum
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika     Volume:  51     ISSN:  0011-8516     ISO Abbreviation:  J. Dent. Assoc. S. Afr.     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1998-03-26     Completed Date:  1998-03-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7505600     Medline TA:  J Dent Assoc S Afr     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  766-70     Citation Subset:  D    
Department of Oral Pathology, University of the Witwatersrand, Johannesburg, Wits.
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MeSH Terms
African Continental Ancestry Group
Cementoma / genetics*,  pathology,  surgery
Dental Cementum / pathology,  surgery
Fibrous Dysplasia of Bone / genetics*,  pathology,  surgery
Jaw Diseases / genetics*,  pathology,  surgery
Jaw Neoplasms / genetics*,  pathology,  surgery
Mandible / pathology,  surgery

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