Document Detail

Familial exudative vitreoretinopathy associated with familial thrombocytopathy.
MedLine Citation:
PMID:  6685528     Owner:  NLM     Status:  MEDLINE    
Two families with familial exudative vitreoretinopathy were studied in which platelet aggregation defects were found in all the affected members. The major defect observed was absent platelet aggregation with arachidonic acid. In addition platelet aggregation with collagen and adrenaline was reduced in one severely affected member. The implication of the platelet aggregation defect in the pathogenesis of this retinal vascular disorder is discussed.
P R Chaudhuri; A R Rosenthal; D B Goulstine; D Rowlands; V E Mitchell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  67     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1984-01-07     Completed Date:  1984-01-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  755-8     Citation Subset:  IM    
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MeSH Terms
Blood Platelet Disorders / genetics*
Eye Diseases / complications,  genetics
Platelet Aggregation
Retinal Diseases / complications,  genetics*
Retinal Vessels
Vitreous Body*

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