| Familial cheiroarthropathy without juvenile onset diabetes mellitus. | |
MedLine Citation:
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PMID: 7163735 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cheiroarthropathy is a recently recognised complication of juvenile onset diabetes mellitus. It comprises inability to extend fully the fingers, contracted tendons, and waxy thickening of the skin overlying the fingers and to a lesser extent the hands. We report two families in which one parent and a number of siblings had the typical features of cheiroarthropathy without juvenile onset diabetes mellitus. The changes developed gradually during childhood and did not progress after adolescence. There were no other abnormal clinical findings, no persistently abnormal laboratory tests, and no association with a specific HLA phenotype. There are some similarities with scleroderma and its recognition is important to prevent unnecessary treatment and to reassure patients. |
Authors:
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D L Scott; J P Delamere; L P Mackintosh; S Jobson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Rheumatology international Volume: 2 ISSN: 0172-8172 ISO Abbreviation: Rheumatol. Int. Publication Date: 1982 |
Date Detail:
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Created Date: 1983-04-15 Completed Date: 1983-04-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8206885 Medline TA: Rheumatol Int Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 141-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Complement C3 / analysis Complement C4 / analysis Diabetes Mellitus, Type 1 / genetics, immunology Female HLA Antigens / analysis Hand Hand Deformities, Acquired / genetics* Humans Joint Diseases / genetics* Male Middle Aged Scleroderma, Systemic / genetics, immunology Syndrome |
| Chemical | |
Reg. No./Substance:
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0/Complement C3; 0/Complement C4; 0/HLA Antigens |
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