| Familial abdominal aortic aneurysm: prevalence and implications for screening. | |
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MedLine Citation:
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PMID: 8270076 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The high prevalence of abdominal aortic aneurysm (AAA) in men over the age of 65 has led to the establishment of ultrasound screening programmes for this group. The apparent familial tendency towards AAA formation suggests that relatives of aneurysm patients may form another subpopulation in whom screening is appropriate. The first degree relatives of 100 consecutive aneurysm patients were identified. Of 110 relatives over 50 years of age, two were known to have had AAA and ultrasound scans were performed on 74, providing information on aortic size for 76 relatives (69%). No further aortic aneurysms (antero-posterior diameter > or = 4.0 cm) were found on scanning. However, nine relatives were demonstrated to have aortic dilatation (2.5-3.9 cm). Aortic dilatation was observed in 21% of male first degree relatives over 50 years of age, affecting 27% of sons and 17% of brothers. Only 4% of the sisters and none of the daughters were found to have aortic dilatation. The prevalence of aortic enlargement seems to be sufficiently high amongst male first degree relatives of AAA patients over 50 years of age to justify aortic screening. |
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Authors:
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D C Adams; B R Tulloh; S W Galloway; E Shaw; A J Tulloh; K R Poskitt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of vascular surgery Volume: 7 ISSN: 0950-821X ISO Abbreviation: Eur J Vasc Surg Publication Date: 1993 Nov |
Date Detail:
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Created Date: 1994-02-03 Completed Date: 1994-02-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8709440 Medline TA: Eur J Vasc Surg Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 709-12 Citation Subset: IM |
Affiliation:
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Department of Vascular Surgery, Cheltenham General Hospital, Gloucestershire, U.K. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Aortic Aneurysm, Abdominal / epidemiology, genetics*, prevention & control England / epidemiology Feasibility Studies Female Humans Male Mass Screening Middle Aged Prevalence Risk Factors Ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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