| Familial prevalence of celiac disease. | |
| | |
MedLine Citation:
|
PMID: 20554512 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Background and objective: Serological screening enables us to detect patients of celiac disease (CD) before they develop serious complications. This study was planned to assess the prevalence of CD in the family members of index cases by serological screening. Patients and Methods: A prospective study was conducted on 50 children diagnosed to be having CD. Serological screening of the family members of index cases was done and those showing positivity for the screening tests were further subjected to endoscopic duodenal biopsy for histopathological examination. Results: A total of 164 members of 50 celiac families were initially screened for antibodies. Antibody picked up 32.9% by IgG anti-gliadin (AGA), 20.7% by endomysial antibody, 19.5% by tissue transglutaminase and 14.6% IgA AGA as seropositive for CD. Endoscopic findings characteristics for CD were present in only eight family members. Conclusion: Family members of CD cases represent potential cases of CD. |
| | |
Authors:
|
Babu Ram Thapa; Pawan Rawal; Bharat Sapra; Kim Vaiphei; Chander Kanwal Nain; Kartar Singh |
Publication Detail:
|
Type: Journal Article Date: 2010-06-16 |
Journal Detail:
|
Title: Journal of tropical pediatrics Volume: 57 ISSN: 1465-3664 ISO Abbreviation: J. Trop. Pediatr. Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-01-31 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8010948 Medline TA: J Trop Pediatr Country: England |
Other Details:
|
Languages: eng Pagination: 45-50 Citation Subset: IM |
Affiliation:
|
Division of Pediatric Gastroenterology Hepatology and Nutrition, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Acupuncture improves exercise tolerance of patients with heart failure: a placebo-controlled pilot s...
Next Document: A Clinical Study of Hospitalized H1N1 Infected Children in Western Rajasthan.