Document Detail

Familial Mediterranean fever with chronic ascites: a case report and a review of literature.
MedLine Citation:
PMID:  19151977     Owner:  NLM     Status:  MEDLINE    
Familial Mediterranean fever (FMF) is an autosomal recessive inflammatory disease especially seen in Turks, Sephardic Jews, Armenians, and Arabs. Peritoneal and pleural inflammation, arthritis, erysipelas-like erythema, and arthralgia are well-known features of FMF. A small amount of peritoneal fluid collection can be seen during peritoneal attacks in FMF patients, but chronic ascites is a rather rare complication. We herein report a female FMF patient who developed chronic ascites. She was compound heterozygote for M694V/M680I mutation of the MEFV gene. Aspiration of the ascites fluid revealed a small amount of erythrocytes and mesothelial cells. After dose adjustment of colchicine the amount of ascites decreased. In conclusion, FMF should be considered in the differential diagnosis of chronic ascites in populations where the disease is endemic.
Kemal Ureten; Ahmet Bostanci; Erdem Akbal; G??ls??m G??n??lalan; Mustafa Ozbek; Mehmet Akif Ozt??rk
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-01-17
Journal Detail:
Title:  Rheumatology international     Volume:  29     ISSN:  1437-160X     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-08-19     Completed Date:  2010-02-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1477-80     Citation Subset:  IM    
Department of Rheumatology, Ministry of Health Diskapi Yildirim Beyazit Research and Educational Hospital, Turan G??ne??, Cankaya, Ankara, Turkey.
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MeSH Terms
Ascites / diagnosis*,  etiology
Chronic Disease
Cytoskeletal Proteins / genetics
Diagnosis, Differential
Familial Mediterranean Fever / complications,  diagnosis*,  genetics
Mutation / genetics
Tomography, X-Ray Computed
Reg. No./Substance:
0/Cytoskeletal Proteins; 0/marenostrin

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