Document Detail

Fame comes at a cost: a Canadian analysis of procedural costs in use of pressure wire to guide multivessel percutaneous coronary intervention.
MedLine Citation:
PMID:  21459275     Owner:  NLM     Status:  MEDLINE    
The FAME-study authors claimed that fractional flow reserve (FFR)-guided multivessel percutaneous coronary intervention (PCI) achieved superior clinical outcome and lower cost compared with no FFR. However, patients were intended to undergo multivessel PCI with drug eluting stents prior to randomization, which tipped the cost-analysis heavily in favour of FFR. We retrospectively evaluated 100 intermediate coronary lesions assessed by FFR, and determined whether to perform PCI based on visual angiographic assessment alone. We found that angiographic-guided treatment underestimated functional significance of intermediate lesions, resulting in fewer implanted stents compared to FFR guidance. This, in addition to the pressure wire cost, increased procedural expenditure 2- to 3-fold when using FFR-guidance.
Stephen P Hoole; Michael D Seddon; Rohan S Poulter; G B John Mancini; David A Wood; Jacqueline Saw
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  27     ISSN:  1916-7075     ISO Abbreviation:  Can J Cardiol     Publication Date:    2011 Mar-Apr
Date Detail:
Created Date:  2011-04-04     Completed Date:  2011-06-07     Revised Date:  2011-11-07    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  262.e1-2     Citation Subset:  IM    
Copyright Information:
Copyright © 2011. Published by Elsevier Inc.
Vancouver General Hospital, Vancouver, British Columbia, Canada.
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MeSH Terms
Angioplasty, Balloon, Coronary / economics*,  instrumentation
Coronary Angiography / economics
Coronary Artery Disease / diagnosis,  economics,  therapy*
Costs and Cost Analysis
Equipment Design
Fractional Flow Reserve, Myocardial*
Health Care Costs*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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