Document Detail


False-positive urine pregnancy test in a woman with adenomysosis.
MedLine Citation:
PMID:  19857433     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present a case of a 39-year-old woman presenting to the emergency department with persistent vaginal bleeding with myoma and endometrium thickness. The qualitative urine human chorionic gonadotropin (hCG) showed positive result, however, the quantitative serum hCG had negative result. The negative serum hCG result suggests that the false-positive result was not caused by elevated circulating hCG. According to the urine hCG one-step pregnancy device, 1 mg/dL of hemoglobin may not interference the pregnancy result. Nevertheless, we found that the hemoglobin level was 40 mg/dL in the urine specimen. We designed a in vitro experiment to evaluate the effects of hemoglobin on urine pregnancy test. The concentrations of hemoglobin from 5 to 500 mg/dL did not yield a positive urine pregnancy test. On the basis of our findings, the false positive pregnancy test was not caused by hemoglobin. It is important to confirm a suspected false-positive urine hCG test using a quantitative serum hCG test. Although it is not certain the mechanism for false positive reaction in this peculiar sample, the ACON urine hCG one-step pregnancy will occasionally yield a false-positive result in this class of patients.
Authors:
Tze Kiong Er; Chein-Hua Chiang; Bin Hong Cheng; Fu Jung Hong; Ching Ping Lee; Miguel Angel Ruiz Ginés
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-09-22
Journal Detail:
Title:  The American journal of emergency medicine     Volume:  27     ISSN:  1532-8171     ISO Abbreviation:  Am J Emerg Med     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-27     Completed Date:  2009-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309942     Medline TA:  Am J Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1019.e5-7     Citation Subset:  IM    
Affiliation:
Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Department of Laboratory Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan. tzekiong@totalbb.net.tw
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MeSH Terms
Descriptor/Qualifier:
Adult
Chorionic Gonadotropin / blood,  urine
Endometriosis / blood,  urine*
False Positive Reactions
Female
Humans
Pregnancy / urine*
Pregnancy Tests / methods*
Urinalysis / methods
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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