Document Detail


False-positive pregnancy test associated with gonadoblastoma.
MedLine Citation:
PMID:  10754126     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Gonadoblastomas are known to be hormonally active tumors that occur in streak or dysgenetic gonads of patients with intersex abnormalities. Several reports document their ability to produce beta-human chorionic gonadotropin (HCG), but none have documented an elevated peripheral serum beta-HCG. We report on the case of a patient with pure gonadal dysgenesis with XY karyotype who was found to have an elevated peripheral serum beta-HCG after a positive pregnancy test. Knowledge of gonadoblastoma's potential to elevate serum beta-HCG levels may prevent unnecessary searches for other causes.
Authors:
F J Schanne; C S Cooper; D A Canning
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Urology     Volume:  54     ISSN:  1527-9995     ISO Abbreviation:  Urology     Publication Date:  1999 Jul 
Date Detail:
Created Date:  2000-04-19     Completed Date:  2000-04-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  162     Citation Subset:  IM    
Affiliation:
Division of Pediatric Urology, Children's Hospital of Philadelphia, PA, 19104 USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Chorionic Gonadotropin, beta Subunit, Human / blood*
False Positive Reactions
Female
Gonadal Dysgenesis, 46,XY / blood,  complications*
Gonadoblastoma / blood*,  diagnosis*,  etiology
Humans
Ovarian Neoplasms / blood*,  diagnosis*,  etiology
Pregnancy Tests
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin, beta Subunit, Human

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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