Document Detail


False-negative hydroxyamphetamine (Paredrine) test in acute Horner's syndrome.
MedLine Citation:
PMID:  8956653     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To describe a false-negative hydroxyamphetamine test. METHOD: Two patients with acute unilateral Horner's syndrome whose pupils initially dilated equally to hydroxyamphetamine had pharmacologic localization to the postganglionic nerve in the second week following the onset of symptoms. RESULTS: Neuroimaging confirmed the postganglionic location in both cases. CONCLUSION: Falsely negative localization with hydroxyamphetamine can occur during the first week after injury, during which time the function of the boutons at the presynaptic terminal is lost.
Authors:
S P Donahue; P J Lavin; K Digre
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  122     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1996-12-31     Completed Date:  1996-12-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  900-1     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN, USA, sean.donahue@mcmail.vanderbilt.edu
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
False Negative Reactions
Horner Syndrome / diagnosis*
Humans
Male
Middle Aged
Mydriatics / diagnostic use*
Ophthalmic Solutions
Ophthalmology / methods
Predictive Value of Tests
Pupil / drug effects
p-Hydroxyamphetamine / diagnostic use*
Chemical
Reg. No./Substance:
0/Mydriatics; 0/Ophthalmic Solutions; 103-86-6/p-Hydroxyamphetamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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