| False-Positive Bone Metastases on PET/CT Secondary to Sarcoidosis in a Patient With Rectal Cancer. | |
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MedLine Citation:
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PMID: 22310266 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Patient with newly diagnosed rectal cancer underwent staging PET/CT that showed an intensely [F-18]-fluoro-2-deoxy-D-glucose (FDG)-avid rectal tumor, but also multifocal, intensely FDG-avid mediastinal lymphadenopathy and skeletal foci. The bone foci had no corresponding lytic or blastic lesions on CT. There were mildly FDG-avid reticulonodular opacities in both lungs. This apparent metastatic distribution pattern was highly atypical for rectal cancer; therefore, biopsy was recommended. It showed granulomatous disease in a lymph node and the bone marrow, indicating sarcoidosis. Bone involvement in sarcoidosis is rare, but can lead to the false-positive appearance of metastatic disease on PET/CT. |
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Authors:
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Kenneth M Montini; Mark Tulchinsky |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical nuclear medicine Volume: 37 ISSN: 1536-0229 ISO Abbreviation: Clin Nucl Med Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-02-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7611109 Medline TA: Clin Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 307-10 Citation Subset: IM |
Affiliation:
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From the Department of Radiology, Penn State Hershey Medical Center, Hershey, PA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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