Document Detail


Fallopian tube sperm perfusion: first clinical experience.
MedLine Citation:
PMID:  1447366     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have developed an insemination method using a large (4 ml) volume of the inseminate. This method incorporates ovarian stimulation, isolation of an optimal number of motile spermatozoa and, finally, Fallopian tube sperm perfusion (FSP). In a clinical study, 139 couples with various causes of infertility, had a total of 239 treatment cycles. The pregnancy rate per treatment in groups with endometriosis, ovulation disorders, tubal impairment, combined male and female factors and subnormal sperm quality were low, ranging from 2.7% to 7.7%. In patients with unexplained infertility, the pregnancy rate per treatment was 26.9% and for this group, the pregnancy rate in the first treatment cycle was 37.3%. In the cervical hostility group, two pregnancies occurred after five treatments. FSP seems to be a favourable treatment for couples with cervical hostility or unexplained infertility. About half of the women in these groups conceived after three treatment cycles. FSP is easier to perform and is less expensive than other methods of assisted procreation, such as in vitro fertilization and gamete intra-Fallopian transfer.
Authors:
J A Kahn; V von Düring; A Sunde; T Sørdal; K Molne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  7 Suppl 1     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-12-30     Completed Date:  1992-12-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  19-24     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, University Hospital of Trondheim, Norway.
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MeSH Terms
Descriptor/Qualifier:
Adult
Fallopian Tubes
Female
Humans
Infertility / etiology,  therapy
Insemination, Artificial, Homologous / methods*
Male
Middle Aged
Perfusion
Spermatozoa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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