Fall and balance outcomes after an intervention to promote leg strength, balance, and walking in people with diabetic peripheral neuropathy: "feet first" randomized controlled trial.

Fall and balance outcomes after an intervention to promote leg strength, balance, and walking in people with diabetic peripheral neuropathy: "feet first" randomized controlled trial.

MedLine Citation:	PMID: 20798179 Owner: NLM Status: MEDLINE
Abstract/OtherAbstract:	BACKGROUND: Weight-bearing exercise has been discouraged for people with diabetes mellitus and peripheral neuropathy (DM+PN). However, people with diabetes mellitus and insensate feet have an increased risk of falling. Lower-extremity exercise and balance training reduce fall risk in some older adults. It is unknown whether those with neuropathy experience similar benefits. OBJECTIVE: As part of a study of the effects of weight-bearing exercise on foot ulceration in people with DM+PN, the effects of a lower-extremity exercise and walking intervention on balance, lower-extremity strength (force-generating capacity), and fall incidence were determined. Design The study was an observer-masked, 12-month randomized controlled trial. SETTING: Part 1 of the intervention took place in physical therapy offices, and part 2 took place in the community. PATIENTS: The participants were 79 people who were mostly sedentary, who had DM+PN, and who were randomly assigned to either a control group (n=38) or an intervention group (n=41). Intervention Part 1 included leg strengthening and balance exercises and a graduated, self-monitored walking program; part 2 included motivational telephone calls. Both groups received regular foot care, foot care education, and 8 sessions with a physical therapist. MEASUREMENTS: The measurements collected were strength, balance, and participant-reported falls for the year after enrollment. RESULTS: There were no statistically significant differences between the groups for falls during follow-up. At 12 months, there was a small increase in the amount of time that participants in the intervention group could stand on 1 leg with their eyes closed. No other strength or balance measurements differed between the groups. LIMITATIONS: The study was designed to detect differences in physical activity, not falls. The intensity of the intervention was insufficient to improve strength and balance in this population. CONCLUSIONS: The training program had a minimal effect on participants' balance and lower-extremity strength. Increasing weight-bearing activity did not alter the rate of falling for participants in the intervention group relative to that for participants in the control group. People who are sedentary and who have DM+PN appear to be able to increase activity without increasing their rate of falling.

Authors:	Robin L Kruse; Joseph W Lemaster; Richard W Madsen
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Publication Detail:	Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2010-08-26
Journal Detail:	Title: Physical therapy Volume: 90 ISSN: 1538-6724 ISO Abbreviation: Phys Ther Publication Date: 2010 Nov
Date Detail:	Created Date: 2010-11-02 Completed Date: 2010-12-08 Revised Date: -
Medline Journal Info:	Nlm Unique ID: 0022623 Medline TA: Phys Ther Country: United States
Other Details:	Languages: eng Pagination: 1568-79 Citation Subset: AIM; IM
Affiliation:	Department of Family and Community Medicine, School of Medicine, University of Missouri, MA306 Medical Sciences Bldg, Columbia, MO 65212, USA. kruser@missouri.edu
Data Bank Information
Bank Name/Acc. No.:	ClinicalTrials.gov/NCT00286598
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MeSH Terms
Descriptor/Qualifier:	Accidental Falls / statistics & numerical data* Diabetic Nephropathies / physiopathology* Disability Evaluation Exercise / physiology Female Humans Lower Extremity / physiology* Male Middle Aged Muscle Strength / physiology* Postural Balance / physiology* Walking / physiology*

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