Document Detail


Failure of naloxone to reverse vascular neurologic deficits.
MedLine Citation:
PMID:  6685246     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Naloxone failed to improve motor strength in any of 19 patients with acute stroke, even though 4 patients eventually demonstrated complete recovery. Two patients worsened, and sensory abnormalities increased in two others. Motor tone increased in eight patients. Naloxone amelioration of stroke deficits is therefore not common, and this treatment may not be entirely benign.
Authors:
J R Cutler; D E Bredesen; R Edwards; R P Simon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  33     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1517-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cerebrovascular Disorders / drug therapy*
Female
Humans
Male
Middle Aged
Naloxone / therapeutic use*
Nervous System Diseases / drug therapy
Chemical
Reg. No./Substance:
465-65-6/Naloxone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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