Document Detail

Failure of naloxone to alter exercise-induced growth hormone and prolactin release in normal men.
MedLine Citation:
PMID:  7226565     Owner:  NLM     Status:  MEDLINE    
Growth hormone and prolactin levels during standardized exercise tests were measured in ten normal male volunteers, with and without previous intravenous administration of 4 mg naloxone. No significant influence of naloxone on hormone release could be observed. The lack of effect indicates that an opioid pathway is not involved in exercise-induced growth hormone and prolactin release in humans, in contrast to that in rats.
G Mayer; J Wessel; J Köbberling
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical endocrinology     Volume:  13     ISSN:  0300-0664     ISO Abbreviation:  Clin. Endocrinol. (Oxf)     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-07-09     Completed Date:  1981-07-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0346653     Medline TA:  Clin Endocrinol (Oxf)     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  413-6     Citation Subset:  IM    
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MeSH Terms
Growth Hormone / blood,  secretion*
Naloxone / pharmacology*
Physical Exertion*
Prolactin / blood,  secretion*
Secretory Rate / drug effects
Reg. No./Substance:
465-65-6/Naloxone; 9002-62-4/Prolactin; 9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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