| Failure of mycophenolate mofetil therapy in primary refractory nephrotic syndrome. | |
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MedLine Citation:
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PMID: 17173257 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mycophenolate mofetil (MMF) has been suggested as a promising therapeutic agent in the treatment of idiopathic nephrotic syndrome. Two patients with persistent nephrotic syndrome, secondary to minimal change disease and idiopathic membranous nephropathy, respectively, who were steroid-, cyclophosphamide- and cyclosporine-resistant, were treated with MMF during a 6-12-month period. In these cases there was no beneficial effect from treatment with MMF. Therapy was stopped after 6 months in case 1 and after 12 months in case 2 due to the persistence of proteinuria. |
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Authors:
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Veronica Baglio; Gabriella Pecci; Concetta Gangemi; Giusi Barresi; Santo Morabito; Alessandro Pierucci |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of nephrology Volume: 19 ISSN: 1121-8428 ISO Abbreviation: J. Nephrol. Publication Date: 2006 Nov-Dec |
Date Detail:
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Created Date: 2006-12-18 Completed Date: 2007-04-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9012268 Medline TA: J Nephrol Country: Italy |
Other Details:
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Languages: eng Pagination: 819-24 Citation Subset: IM |
Affiliation:
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Division of Nephrology, Department of Clinical Sciences, Policlinico Umberto I, Rome, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*, adverse effects Drug Resistance* Humans Male Middle Aged Mycophenolic Acid / administration & dosage, adverse effects, analogs & derivatives* Nephrotic Syndrome / drug therapy* Proteinuria / drug therapy Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 128794-94-5/mycophenolate mofetil; 24280-93-1/Mycophenolic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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