Document Detail


Failure of angiotensin II inhibitor to modify hyperacute rejection.
MedLine Citation:
PMID:  1098189     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of angiotensin II inhibitor (sar1,gly8 angiotensin II) upon the pig-to-dog (10 pigs to 20 dogs) modified renal xenograft model has been studied. The angiotensin II inhibitor does not prevent hyperacute rejection (HAR). This implies that the vasocaonstriction which occurs during the HAR is not related to high levels of angiotensin II.
Authors:
M A Haberal; M M Ppovtzer; K M McDonald; S J Guggenheim; R S Picache; C W Putman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Surgery     Volume:  78     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1975 Aug 
Date Detail:
Created Date:  1975-11-07     Completed Date:  1975-11-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  149-53     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Angiotensin II / administration & dosage,  analogs & derivatives*,  antagonists & inhibitors,  pharmacology
Animals
Biopsy
Blood Cell Count
Dogs
Glycine
Graft Rejection*
Hematocrit
Infusions, Parenteral
Kidney / pathology
Kidney Transplantation*
Perfusion
Regional Blood Flow / drug effects
Renal Veins
Renin / blood
Sarcosine
Sodium Chloride
Swine
Transplantation, Heterologous
Urine / drug effects
Chemical
Reg. No./Substance:
107-97-1/Sarcosine; 11128-99-7/Angiotensin II; 56-40-6/Glycine; 7647-14-5/Sodium Chloride; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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