Document Detail

Failed repeated thrombolysis requiring left ventricular assist device pump exchange.
MedLine Citation:
PMID:  22718366     Owner:  NLM     Status:  Publisher    
A 51 year-old male with untreated hepatitis C infection, cirrhosis and dilated cardiomyopathy with a HeartMate II LVAD presented with right heart failure and cardiogenic shock, INR of 7, hemolysis and renal failure. Acute LVAD thrombosis was suspected. Alteplase was injected into the inflow cannula of the LVAD with little effect. Intravenous Alteplase was given but failed to restore an adequate pump output, resulting in the need for emergency pump exchange. The patient had an uncomplicated post-operative recovery and was discharged uneventfully. Inspection of the pump identified a thrombus wedged between the spines of the impeller. Our case highlights the challenges in managing pump thrombosis which is often resistant to thrombolysis and may instead rely upon prompt surgical intervention to be resolved. © 2012 Wiley Periodicals, Inc.
Gilbert H L Tang Md; Michael C Kim Md; Sean P Pinney Md; Anelechi C Anyanwu Md
Related Documents :
16168276 - Aspirin use in chronic heart failure: what should we recommend to the practitioner?
9296466 - Low-molecular-weight heparin (fragmin) during instability in coronary artery disease (f...
11177336 - Thrombus formation on atherosclerotic plaques: pathogenesis and clinical consequences.
11072276 - New strategies in the management of acute coronary syndromes.
3594506 - Ventricular tachyarrhythmia initiation in a canine model of recent myocardial infarctio...
8443906 - Signal-averaged electrocardiogram. improved identification of patients with ventricular...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-21
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  -     ISSN:  1522-726X     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Department of Cardiothoracic Surgery, New York, New York, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Refreshing labioplasty techniques for plastic surgeons.
Next Document:  Major determinants of myocardial injury after pulmonary vein isolation with radiofrequency ablation.