| Factors which influence alterations of phosphates and pH in exercising human skeletal muscle: measurement error, reproducibility, and effects of fasting, carbohydrate loading, and metabolic acidosis. | |
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MedLine Citation:
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PMID: 7799999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Previous studies have shown considerable variability in the metabolic response of human skeletal muscle during a standardized exercise protocol. The goal of these studies was to investigate the factors responsible for the broad range of metabolic changes produced by fatiguing exercise. Experiments were performed to quantitate the measurement error of 31P nuclear magnetic resonance spectroscopy of human muscle, the reproducibility of changes within a single subject, and the effects of fasting, carbohydrate loading, and metabolic acidosis. The results show that none of these factors appear to be responsible for the wide variation between subjects. However, the effects of training and genetic factors were not investigated and are likely to be responsible for the substantial variability between subjects. |
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Authors:
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R G Miller; P J Carson; R S Moussavi; A Green; A Baker; M D Boska; M W Weiner |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Muscle & nerve Volume: 18 ISSN: 0148-639X ISO Abbreviation: Muscle Nerve Publication Date: 1995 Jan |
Date Detail:
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Created Date: 1995-01-23 Completed Date: 1995-01-23 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 7803146 Medline TA: Muscle Nerve Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 60-7 Citation Subset: IM; S |
Affiliation:
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Department of Neurology, California Pacific Medical Center, San Francisco 94118. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acidosis
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metabolism Adult Dietary Carbohydrates / pharmacology Fasting Female Humans Hydrogen / metabolism* Hydrogen-Ion Concentration Isometric Contraction Male Middle Aged Muscle, Skeletal / metabolism*, physiology Phosphates / metabolism* Physical Exertion* Reproducibility of Results |
| Grant Support | |
ID/Acronym/Agency:
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R01 DK 33293-05/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Dietary Carbohydrates; 0/Phosphates; 1333-74-0/Hydrogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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