| Factors related to a clinically silent peri-procedural drop in hemoglobin with coronary and peripheral vascular interventions. | |
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MedLine Citation:
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PMID: 22003001 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Clinically evident and subclinical peri-procedural bleeding following interventional therapies are associated with adverse cardiovascular outcomes. The risk factors for clinically evident bleeding have been well described. Despite the well-documented association of adverse outcomes for patients with a subclinical peri-procedural hemoglobin drop, the clinical predictors have not yet been defined. We identified 1176 consecutive patients with a subclinical drop in hemoglobin (fall of ≥ 1 g/dl in patients without clinical bleeding) following percutaneous coronary interventions (PCI) and peripheral vascular interventions (PVI). Multivariate logistic regression analysis was performed. A subclinical peri-procedural hemoglobin drop ≥ 1 g/dl was identified in 41% (400/972) of PCI and in 49% (213/435) of PVI. More than one access site predicted a higher risk of a subclinical drop in hemoglobin in both groups. A body mass index ≥ 30 predicted a lower risk of a subclinical drop in hemoglobin in both groups. For PCI, creatinine clearance < 60 ml/min was associated with a higher risk of a subclinical drop in hemoglobin. In conclusion, clinically silent peri-procedural hemoglobin fall ≥ 1 g/dl is common in patients undergoing both coronary and peripheral percutaneous intervention. Predictors identified in our study will need prospective validation. |
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Authors:
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Zehra Jaffery; Christopher J White; Tyrone J Collins; Mark A Grise; J Stephen Jenkins; Paul W McMullan; Rajan A Patel; John P Reilly; Stanley N Thornton; Stephen R Ramee |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Vascular medicine (London, England) Volume: 16 ISSN: 1477-0377 ISO Abbreviation: Vasc Med Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610930 Medline TA: Vasc Med Country: England |
Other Details:
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Languages: eng Pagination: 354-9 Citation Subset: IM |
Affiliation:
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Department of Cardiology, Ochsner Heart and Vascular Institute, John Ochsner Clinic Foundation, New Orleans, LA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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