| Factors predictive for in-hospital mortality following percutaneous coronary intervention. | |
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MedLine Citation:
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PMID: 18848686 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Despite advances in procedures for percutaneous coronary intervention (PCI) and enhancement of materials and adjunctive therapy, postprocedural mortality remains a possible adverse outcome after PCI. AIMS: To assess factors independently associated with in-hospital mortality in patients referred for PCI. METHODS: Between January 2004 and December 2005, 4074 PCI were performed in our University Hospital, with 70 deaths registered either during the procedure or during the in-hospital stay. The 70 patients who died were age- and sex-matched with 70 controls in a case-control design study. Clinical and angiographic characteristics at hospital admission were collected from the patients' medical files. RESULTS: The cumulative incidence rate for in-hospital mortality was 1.72%. Variables positively and significantly associated with in-hospital mortality were severe renal failure (55.7% in cases versus 12.9% in controls, p<0.0001), cardiac failure (26.1% versus 10.1%, p=0.01), ST-segment elevation myocardial infarction (STEMI) (70.6% versus 31.4%, p<0.0001), proximal coronary lesion (72.9% versus 40.0%, p<0.0001) and angiographically visible thrombus (14.3% versus 4.3%, p=0.04). Conversely, history of coronary heart disease, smoking and dyslipidemia were less frequent among cases. In multivariable analysis, the adjusted odds ratios (OR) for in-hospital death were 4.89 (95% confidence interval [CI] 1.96-12.2, p<0.001) in STEMI versus non-STEMI, 4.28 (95% CI 1.73-10.6, p<0.01) in those with a proximal coronary lesion, and 9.77 (95% CI 3.42-27.9, p<0.0001) in patients with severe renal failure. CONCLUSION: STEMI, proximal coronary lesion, and renal failure at admission are identified as particular settings associated with a higher probability of in-hospital mortality after PCI. |
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Authors:
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Walid Zouaoui; Horma Ouldzein; Nicolas Boudou; Nicolas Dumonteil; Vanina Bongard; Cécile Baixas; Michel Galinier; Jérôme Roncalli; Meyer Elbaz; Jacques Puel; Jean-Marie Fauvel; Didier Carrié |
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Publication Detail:
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Type: Journal Article Date: 2008-08-22 |
Journal Detail:
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Title: Archives of cardiovascular diseases Volume: 101 ISSN: 1875-2136 ISO Abbreviation: Arch Cardiovasc Dis Publication Date: 2008 Jul-Aug |
Date Detail:
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Created Date: 2008-10-13 Completed Date: 2009-03-26 Revised Date: 2011-04-25 |
Medline Journal Info:
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Nlm Unique ID: 101465655 Medline TA: Arch Cardiovasc Dis Country: Netherlands |
Other Details:
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Languages: eng Pagination: 443-8 Citation Subset: IM |
Affiliation:
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Pôle cardiovasculaire et métabolique, fédération de cardiologie, CHU de Toulouse Rangueil, Toulouse, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Angioplasty, Balloon, Coronary / mortality* Female Hospital Mortality* Humans Male Middle Aged Prognosis |
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