Document Detail

Factors predictive of follow-up clinic attendance and developmental outcome in a regional cohort of very low birth weight infants.
MedLine Citation:
PMID:  7694456     Owner:  NLM     Status:  MEDLINE    
This population-based, retrospective cohort study of very low birth weight infants was undertaken to: 1) identify factors associated with nonattendance for follow-up, 2) estimate the prevalence of cerebral palsy at age > or = 18 months, and 3) model the prognostic association between prenatal and perinatal risk markers and cerebral palsy. The sample included 496 surviving very low birth weight infants born in 32 hospitals in Southwest Ontario between January 1982 and December 1986. Multivariate analyses were performed using the proportional odds regression model. Loss to follow-up was more likely among those with mothers < 20 years of age, those with unmarried mothers, and those not born in a tertiary center. Loss to follow-up was less likely for those with neonatal anemia and those of lower birth weight. Motor development of the 369 children who were followed at least 18 months was classified into one of three categories: normal, suspect, or cerebral palsy. Multivariate analysis revealed that factors predictive of poorer outcome were intraventricular hemorrhage, unmarried mother, male sex, recurrent apnea, and hydrocephalus. The finding that unmarried status was associated with loss to follow-up and was also an important predictor of cerebral palsy suggests that it is important for follow-up clinics to identify ways of assisting this population to remain in contact with the clinic.
M K Campbell; E Halinda; M J Carlyle; A M Fox; L A Turner; G W Chance
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of epidemiology     Volume:  138     ISSN:  0002-9262     ISO Abbreviation:  Am. J. Epidemiol.     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1993-12-14     Completed Date:  1993-12-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7910653     Medline TA:  Am J Epidemiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  704-13     Citation Subset:  IM    
Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada.
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MeSH Terms
Analysis of Variance
Birth Weight
Cerebral Palsy / epidemiology*
Cohort Studies
Developmental Disabilities / epidemiology*
Follow-Up Studies
Infant, Low Birth Weight*
Infant, Newborn
Infant, Newborn, Diseases
Marital Status
Odds Ratio
Patient Dropouts*
Regression Analysis
Retrospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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