| Factors predicting the outcome of intraarterial thrombolysis in peripheral arterial and graft occlusions. | |
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MedLine Citation:
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PMID: 8845257 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To determine the association between successful intraarterial thrombolysis and the following factors: sex, age, symptoms, duration of symptoms, length of occlusion, conduit type, runoff, and catheter localization. MATERIAL AND METHODS: Forty-six patients with acute or subacute occlusions of peripheral native arteries and grafts were treated with continuous intraarterial infusion of streptokinase or urokinase. A univariate chi-square test and logistic regression analysis were used. RESULTS: Successful lysis was achieved in 27 of 46 patients (59%). The logistic regression analysis revealed a significant association between successful thrombolysis and good runoff (p < 0.01). A catheter position above the occlusion resulted in lysis in only one of 11 patients. The variables rest pain and claudication were slightly significant (p = 0.07). None of the other variables were significant, but a trend toward a separate effect of duration of occlusion was found. CONCLUSION: Good runoff and intrathrombotic infusion are virtual necessities in obtaining a positive immediate outcome in peripheral arterial and graft occlusions. In our study, other factors were less important. |
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Authors:
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G Sandbaek; L E Staxrud; L Rosen; D Bay; M Stiris; T Gjølberg |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta radiologica (Stockholm, Sweden : 1987) Volume: 37 ISSN: 0284-1851 ISO Abbreviation: Acta Radiol Publication Date: 1996 May |
Date Detail:
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Created Date: 1996-10-24 Completed Date: 1996-10-24 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8706123 Medline TA: Acta Radiol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 299-304 Citation Subset: IM |
Affiliation:
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Department of Radiology, Aker University Hospital, Oslo, Norway. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Arterial Occlusive Diseases / drug therapy*, epidemiology, radiography Chi-Square Distribution Female Graft Occlusion, Vascular / drug therapy*, epidemiology, radiography Humans Infusions, Intra-Arterial Logistic Models Male Peripheral Vascular Diseases / drug therapy*, epidemiology, radiography Plasminogen Activators / administration & dosage* Risk Factors Streptokinase / administration & dosage* Thrombolytic Therapy* / methods Treatment Outcome Urokinase-Type Plasminogen Activator / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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EC 3.4.-/Streptokinase; EC 3.4.21.-/Plasminogen Activators; EC 3.4.21.73/Urokinase-Type Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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