| Factors predicting ante- and postnatal growth. | |
| | |
MedLine Citation:
|
PMID: 18043501 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Human growth is a continuous process. Studies defining factors influencing growth focus on discrete time points (e.g., birth), overlooking the conditional nature of the process. One thousand six hundred fifty Caucasian mothers who gave birth at term after an uncomplicated singleton pregnancy were studied using conditional analysis. Infant height, weight, and head circumference were obtained at birth and 6 mo of age. Data analysis, conditional upon birth size, was conducted as a stepped consideration of factors influencing phases of fetal and infant growth beginning with determinants of placental size. Placental weight was related to birth size. Seven percent of the variance in placental weight was explained by a combination of gestation at delivery, maternal size at first prenatal visit, paternal height (all positive), and increasing parity (negative). When centered on birth weight, 41% of the variance in placental weight was explained by birth weight, length of gestation, smoking during pregnancy (all positive), and a female baby (negative). Maternal and paternal stature equally influenced newborn and infant size. Conditional analysis reveals a series of modifiable (parity, length of gestation, and smoking) and nonmodifiable factors at different stages of the growth process. |
| | |
Authors:
|
Peter C Hindmarsh; Michael P P Geary; Charles H Rodeck; John C P Kingdom; Tim J Cole |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Pediatric research Volume: 63 ISSN: 0031-3998 ISO Abbreviation: Pediatr. Res. Publication Date: 2008 Jan |
Date Detail:
|
Created Date: 2007-12-21 Completed Date: 2008-02-07 Revised Date: 2013-04-29 |
Medline Journal Info:
|
Nlm Unique ID: 0100714 Medline TA: Pediatr Res Country: United States |
Other Details:
|
Languages: eng Pagination: 99-102 Citation Subset: IM |
Affiliation:
|
Developmental Endocrinology Research Group, University College London WC1N 1EH, United Kingdom. p.hindmarsh@ucl.ac.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Birth Weight* Body Height* Cephalometry Child Development / physiology* Fathers Female Fetal Development Gestational Age Head / growth & development* Humans Infant Infant, Newborn Linear Models Longitudinal Studies Male Mothers Organ Size Parity Placenta / growth & development Pregnancy Smoking / adverse effects Time Factors |
| Grant Support | |
ID/Acronym/Agency:
|
G9827821//Medical Research Council; G9827821(62595)//Medical Research Council |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diminished phagocytosis-induced cell death (PICD) in neonatal monocytes upon infection with Escheric...
Next Document: (TA)n UDP-glucuronosyltransferase 1A1 promoter polymorphism in Nigerian neonates.