| Factors influencing oral cavity status during high-dose antineoplastic therapy: a secondary data analysis. | |
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MedLine Citation:
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PMID: 9802057 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE/OBJECTIVES: To identify factors associated with oral cavity status in patients receiving high-dose antineoplastic therapy. DESIGN: Descriptive, correlational secondary analysis. SETTING: Midwestern university oncology special care unit. SAMPLE: 50 males and females, ages 15-69. METHODS: The Oral Assessment Guide (OAG) was used to assess oral cavity status every shift throughout hospitalization. Additional data were collected by chart audit. Correlations and Cox regression analysis were performed. MAIN RESEARCH VARIABLES: Oral cavity status, absolute granulocyte count, blood urea nitrogen (BUN), creatinine, mean OAG score during the preparative regimen (prep-OAG), age, and total body irradiation (TBI). FINDINGS: Elevated BUN and creatinine, higher prep-OAG, older age, and TBI were associated with higher OAG scores. Cox analysis revealed that TBI was predictive of an OAG score > or = 16, and an OAG score > or = 18 was predictive of death by day +20. CONCLUSIONS: Patients who receive TBI and chemotherapy in combination are most likely to experience severely compromised oral cavity status. Those who are older, have poorer oral status, and have decreased renal function are at increased risk. IMPLICATIONS FOR NURSING PRACTICE: High-risk patients must be identified early, and oral assessments and care must be given consistently to decrease morbidity and potential mortality. |
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Authors:
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A M Berger; J Eilers |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Oncology nursing forum Volume: 25 ISSN: 0190-535X ISO Abbreviation: Oncol Nurs Forum Publication Date: 1998 Oct |
Date Detail:
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Created Date: 1998-12-29 Completed Date: 1998-12-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7809033 Medline TA: Oncol Nurs Forum Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1623-6 Citation Subset: IM; N |
Affiliation:
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College of Nursing, University of Nebraska Medical Center, Omaha, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Aged Antineoplastic Agents / adverse effects* Data Interpretation, Statistical Female Humans Male Middle Aged Mouth Mucosa Nursing Assessment Oral Health* Proportional Hazards Models Retrospective Studies Risk Factors Stomatitis / chemically induced*, nursing Whole-Body Irradiation / adverse effects |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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