Document Detail

Factors influencing the incidence and prevalence of food allergy.
MedLine Citation:
PMID:  19663867     Owner:  NLM     Status:  MEDLINE    
Food allergy is an increasing problem in Europe and elsewhere and severe reactions to food are also becoming more common. As food allergy is usually associated with other forms of allergic sensitisation it is likely that many risk factors are common to all forms of allergy. However the potential severity of the disease and the specific public heath measures required for food allergy make it important to identify the specific risk factors for this condition. Food allergy is unusual in that it often manifests itself very early in life and commonly remits with the development of tolerance. Hypotheses that explain the distribution of food allergy include specific genetic polymorphisms, the nature of the allergens involved and the unique exposure to large quantities of allergen through the gut. Progress has been made in developing more specific and testable hypotheses but the evidence for any of these is still only preliminary. Further collaborative research is required to develop an appropriate public health response to this growing problem.
S Cochrane; K Beyer; M Clausen; M Wjst; R Hiller; C Nicoletti; Z Szepfalusi; H Savelkoul; H Breiteneder; Y Manios; R Crittenden; P Burney
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2009-08-05
Journal Detail:
Title:  Allergy     Volume:  64     ISSN:  1398-9995     ISO Abbreviation:  Allergy     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-21     Completed Date:  2010-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7804028     Medline TA:  Allergy     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  1246-55     Citation Subset:  IM    
Safety and Environmental Centre, Unilever Colworth, Colworth Park, Sharnbrook, Bedford, UK.
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MeSH Terms
Allergens / immunology*
Breast Feeding
Cytokines / immunology*,  metabolism
Dendritic Cells / immunology,  metabolism
Food Hypersensitivity / epidemiology*,  genetics,  immunology
Gastrointestinal Tract / immunology*
Immunoglobulin E / blood
T-Lymphocytes / immunology,  metabolism
Reg. No./Substance:
0/Allergens; 0/Cytokines; 37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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