Document Detail

Factors influencing the development of malignant hypertension in Nigeria.
MedLine Citation:
PMID:  10694830     Owner:  NLM     Status:  MEDLINE    
Hypertension prevalence rates remain comparatively low in Nigeria, although the associated morbidity and mortality including that due to malignant hypertension (MHT) is considerable. To determine the factors that may be associated with the development of MHT we compared 74 patients with essential MHT (age 48 +/- 9 years, 59 male, blood pressure (BP) 234 +/- 31/140 +/- 17 mm Hg) with 74, age, gender and BP-matched patients with essential benign hypertension (BHT) (49 +/- 8 years, 60 male, 227 +/- 26/136 +/- 15 mm Hg). Body mass index was higher in the BHT [corrected] group by 1.3 (95% Cl: 0.5 to 2.1, P < 0.01). In the subset (25 MHT, 43 BHT) in whom hypertension had been diagnosed before presentation, duration of hypertension was shorter (P < 0.05) in the MHT group. Patients with MHT, were more likely to have been receiving inadequate therapy in the months before (OR 2.7, 95% Cl: 1.4 to 5.4), showed a decreasing proportion with increasing socio-economic class (chi2 = 5.79, P < 0.02) and had been exposed to a greater degree of stress (OR 3.5, 95% Cl: 1.7 to 7. 1). Smoking (OR 1.1, 0.6 to 2.3), alcohol use (OR 0.9, 0.5 to 1.8) and contraceptive pill use (OR 0.9, 0.1 to 8.6) did not impart excess risk. MHT is associated with the underprivileged and measures aimed at raising the general awareness and the socio-economic level of the people are expected to produce a decline in the incidence of MHT. Journal of Human Hypertension (2000) 14, 171-174.
S Kadiri; B O Olutade; O Osobamiro
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of human hypertension     Volume:  14     ISSN:  0950-9240     ISO Abbreviation:  J Hum Hypertens     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-03-30     Completed Date:  2000-03-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8811625     Medline TA:  J Hum Hypertens     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  171-4     Citation Subset:  IM    
Department of Medicine, University College Hospital, Ibadan, Nigeria.
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MeSH Terms
Blood Pressure
Hypertension / physiopathology
Hypertension, Malignant / etiology*,  physiopathology
Kidney / physiopathology
Middle Aged
Risk Factors
Socioeconomic Factors
Comment In:
J Hum Hypertens. 2000 Mar;14(3):159-61   [PMID:  10694828 ]
Erratum In:
J Hum Hypertens 2000 Aug;14(8):532

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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