Document Detail


Factors influencing the amplitude and frequency of essential tremor.
MedLine Citation:
PMID:  7845397     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Quantitative electromyography (EMG) and triaxial accelerometry were used to measure hand tremor, finger tremor, and forearm motor unit activity in 36 men and 23 women with essential tremor. Hand tremor was studied with and without 300-g mass loading. Tremor and EMG were recorded twice, with a 3-min rest interval, to assess the spontaneous intertrial variability in tremor amplitude, frequency, and motor unit entrainment. In general, the minimum detectable differences in tremor amplitude, frequency, and motor unit entrainment were roughly 30%, 5%, and 10% of the initial sample means, respectively, assuming a sample size of 30 patients, a statistical power of 0.9, and a significance level of 0.05. Linear regression analyses were performed to test the hypotheses that (a) there is an age-associated decrease in tremor frequency that is independent of symptom duration and (b) tremor frequency and motor unit entrainment make independent contributions to tremor amplitude. Our data supported both hypotheses.
Authors:
R J Elble; C Higgins; K Leffler; L Hughes
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Movement disorders : official journal of the Movement Disorder Society     Volume:  9     ISSN:  0885-3185     ISO Abbreviation:  Mov. Disord.     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-03-08     Completed Date:  1995-03-08     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8610688     Medline TA:  Mov Disord     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  589-96     Citation Subset:  IM    
Affiliation:
Department of Neurology, Southern Illinois University School of Medicine, Springfield 62794-9230.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Disability Evaluation
Electromyography*
Female
Hand / innervation
Humans
Male
Middle Aged
Motor Neurons / physiology*
Motor Skills / physiology*
Tremor / physiopathology*
Weight-Bearing / physiology
Grant Support
ID/Acronym/Agency:
NS20973/NS/NINDS NIH HHS; RR05843/RR/NCRR NIH HHS
Comments/Corrections
Erratum In:
Mov Disord 1995 May;10(3):411

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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