Document Detail

Factors influencing R wave amplitude in patients with ischaemic heart disease.
MedLine Citation:
PMID:  6821614     Owner:  NLM     Status:  MEDLINE    
R wave amplitude changes during exercise have been ascribed to alteration in left ventricular volume and their measurement advocated for the improved diagnosis of coronary disease. The reproducibility of exercise QRS changes and their relation to ST segment depression, respiratory pattern, and left ventricular volume during ischaemia were studied in 10 patients with angina and coronary disease. QRS amplitude was measured in a 16 lead precordial map during three identical exercise tests in each patient and left ventricular volume assessed continuously using gated blood pool imaging with a single scintillation probe during manoeuvres to provoke ischaemia. During exercise, QRS amplitude increased or remained unchanged in four patients and fell in six patients in a consistent manner for each patient. R wave amplitude was not affected by changes in respiratory pattern. R wave amplitude did not alter in 33 of 39 episodes of left ventricular volume increase (mean 32%) or decrease (mean 36%) in end-diastolic counts. These findings suggest that precordial R wave changes during ischaemia are not determined primarily by alteration in left ventricular volume or the respiratory pattern. Though reproducible in each patient and following a definite relation to ST segment depression, the variable directional response during exercise suggest that R wave amplitude changes have little diagnostic value.
J E Deanfield; G Davies; F Mongiadi; C Savage; A P Selwyn; K M Fox
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  49     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-03-24     Completed Date:  1983-03-24     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  8-14     Citation Subset:  AIM; IM    
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MeSH Terms
Coronary Disease / physiopathology*
Exercise Test
Heart Ventricles / physiopathology
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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