Document Detail


Factors implicated in the outcome of pregnancies complicated by acute respiratory failure.
MedLine Citation:
PMID:  12971148     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate factors predictive of the outcome of acute respiratory failure during pregnancy. STUDY DESIGN: We retrospectively reviewed the records of all pregnant women diagnosed with acute respiratory failure at a tertiary referral center from January 1, 1995, to September 30, 2000. Maternal characteristics, etiology of respiratory failure and treatment were compared between survivors and nonsurvivors. RESULTS: Twenty patients with acute respiratory failure were identified; 16 of them survived (mortality, 20%). Acute respiratory failure was diagnosed in the postpartum period in 16 (80%), and the majority of cases occurred in the first 2 postpartum days (93.8%). There was no statistically significant difference between the 2 groups in terms of patient characteristics, immediate precipitants of acute respiratory failure (including pneumonia, cardiogenic pulmonary edema, acute respiratory distress syndrome, asthma, pulmonary embolism and amniotic fluid embolism) and laboratory characteristics except for pH. However, patients who manifested disseminated intravascular coagulopathy (DIC) and sepsis as precipitating causes or complications of the immediate precipitating disease entities as well as initial loss of consciousness were predictive of poor maternal outcome. CONCLUSION: The immediate etiology of acute respiratory failure is not predictive of maternal outcome, but lower pH, initial loss of consciousness, DIC and sepsis are risk factors for maternal mortality.
Authors:
Chen-Yu Chen; Chie-Pein Chen; Kuo-Gon Wang; Su-Chen Kuo; Tsung-Hsien Su
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  48     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-09-15     Completed Date:  2004-02-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  641-8     Citation Subset:  IM    
Affiliation:
Division of High Risk Pregnancy, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Graduate Institute of Nurse-Midwifery, National Taipei College of Nursing, Taipei, Taiwan.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Female
Humans
Predictive Value of Tests
Pregnancy
Pregnancy Complications / etiology*,  mortality,  therapy
Pregnancy Outcome*
Puerperal Disorders / etiology*,  mortality,  therapy
Respiratory Insufficiency / etiology*,  mortality,  therapy
Respiratory Therapy
Retrospective Studies
Risk Factors
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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