Document Detail


Factors controlling cardiac neural crest cell migration.
MedLine Citation:
PMID:  20890117     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cardiac neural crest cells originate as part of the postotic caudal rhombencephalic neural crest stream. Ectomesenchymal cells in this stream migrate to the circumpharyngeal ridge and then into the caudal pharyngeal arches where they condense to form first a sheath and then the smooth muscle tunics of the persisting pharyngeal arch arteries. A subset of the cells continue migrating into the cardiac outflow tract where they will condense to form the aorticopulmonary septum. Cell signaling, extracellular matrix and cell-cell contacts are all critical for the initial migration, pauses, continued migration, and condensation of these cells. This review elucidates what is currently known about these factors.
Authors:
Margaret L Kirby; Mary R Hutson
Related Documents :
17301087 - Ptf1a is essential for the differentiation of gabaergic and glycinergic amacrine cells ...
1438217 - Induction of the neural cell adhesion molecule and neuronal aggregation by osteogenic p...
3831217 - Cell lineage labels and region-specific markers in the analysis of inductive interactions.
19959467 - Transforming growth factor-beta regulates basal transcriptional regulatory machinery to...
22120277 - Novel animal glioma models that separately exhibit two different invasive and angiogeni...
20161987 - Nanoparticulate quillaja saponin induces apoptosis in human leukemia cell lines with a ...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Cell adhesion & migration     Volume:  4     ISSN:  1933-6926     ISO Abbreviation:  Cell Adh Migr     Publication Date:    2010 Oct-Dec
Date Detail:
Created Date:  2011-04-18     Completed Date:  2011-06-21     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  101469464     Medline TA:  Cell Adh Migr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  609-21     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Duke University, Durham, NC, USA. mlkirby@duke.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cell Communication
Cell Movement / genetics
Epithelial-Mesenchymal Transition
Extracellular Matrix / metabolism
Ganglia, Autonomic / embryology
Heart / embryology*,  innervation
Humans
Intercellular Junctions / metabolism
Intracellular Signaling Peptides and Proteins / metabolism
Neural Crest / cytology*,  metabolism
Pharynx / blood supply,  embryology,  innervation
Grant Support
ID/Acronym/Agency:
HL036059/HL/NHLBI NIH HHS; HL070140/HL/NHLBI NIH HHS; HL083240/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Intracellular Signaling Peptides and Proteins
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  DNA methylation and epigenetic control of cellular differentiation.
Next Document:  Cross-talk between post-translational modifications regulate life or death decisions by E2F1.