Document Detail

Factors associated with variation in bulk-tank-milk Salmonella Dublin ELISA ODC% in dairy herds.
MedLine Citation:
PMID:  15820114     Owner:  NLM     Status:  MEDLINE    
Our objective was to determine factors that contribute to variation in bulk-tank-milk Salmonella Dublin enzyme-linked immunosorbent assays (ELISA) corrected optic-density measurements (ODC%) in dairy herds. We constructed hierarchical mixed models with repeated bulk-tank-milk ELISA ODC% in 31 Danish dairy herds. Four models included different combinations of explanatory factors, and we compared how well these models described the variation in the data. Herd was included as a random effect nested within Salmonella status and barn type. Detection of Salmonella Dublin or Salmonella Typhimurium by bacteriological culture of individual faecal samples or of slurry samples was associated with higher bulk-tank-milk ELISA ODC%, as was apparent Salmonella prevalence, the mean ELISA ODC% or mean-yield-corrected ELISA ODC% in milk samples collected from all individual cows. However, combinations of risk factors that included number or prevalence of cows with a very high ELISA ODC% provided better models, indicating that the effect of the cow-level explanatory variables on the bulk-tank-milk ELISA ODC% was related to the activity of the infection in the herd. Barn type (loose housing or tie stalls) was not associated with the variation in bulk-tank-milk ELISA ODC% in these models, which might be useful in planning of surveillance programs and intervention strategies.
Liza Rosenbaum Nielsen; Annette Kjaer Ersbøll
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Preventive veterinary medicine     Volume:  68     ISSN:  0167-5877     ISO Abbreviation:  Prev. Vet. Med.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-04-11     Completed Date:  2005-06-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8217463     Medline TA:  Prev Vet Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  165-79     Citation Subset:  IM    
Department of Large Animal Sciences, The Royal Veterinary and Agricultural University, Grønnegårdsvej 8, 1870 Frederiksberg C, Denmark.
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MeSH Terms
Antibodies, Bacterial / analysis
Cattle Diseases / diagnosis,  microbiology*
Enzyme-Linked Immunosorbent Assay / veterinary
Milk / microbiology*
Models, Statistical*
Risk Factors
Salmonella Infections, Animal / diagnosis,  microbiology*
Salmonella enterica / isolation & purification*
Reg. No./Substance:
0/Antibodies, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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