Document Detail

Factors associated with umbilical catheter-related sepsis in neonates.
MedLine Citation:
PMID:  1903588     Owner:  NLM     Status:  MEDLINE    
To determine factors associated with risk for umbilical catheter-related sepsis, we studied neonates with one or more catheters in place for more than 3 days. Among 225 infants with 357 umbilical catheters, catheter-related sepsis occurred in 14 infants (6%). Catheter-related sepsis occurred in 5% of infants with umbilical arterial catheters and in 3% of infants with umbilical venous catheters. Staphylococcal species accounted for 71% of cases of catheter-related sepsis. Multiple logistic regression analysis revealed that very low birth weight and longer duration of antibiotic therapy were significantly associated with risk for umbilical arterial catheter-related sepsis. Increased risk for umbilical venous catheter-related sepsis was best predicted by the simultaneous occurrence of higher birth weight and infusion of hyperalimentation solution. Catheter duration correlated with duration of antibiotic therapy and with infusion of hyperalimentation solution for both types of catheters; however, in the multivariable analysis, duration of catheterization was not found to be a significant independent predictor of risk for catheter-related sepsis for either type of catheter.
S Landers; A A Moise; J K Fraley; E O Smith; C J Baker
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  145     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1991-06-26     Completed Date:  1991-06-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  675-80     Citation Subset:  AIM; IM    
Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030.
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MeSH Terms
Anti-Bacterial Agents / administration & dosage
Birth Weight
Catheterization, Peripheral / adverse effects*
Catheters, Indwelling
Infant, Low Birth Weight / physiology
Infant, Newborn
Multivariate Analysis
Parenteral Nutrition, Total
Risk Factors
Sepsis / etiology*
Staphylococcal Infections / etiology*
Time Factors
Umbilical Arteries*
Umbilical Veins*
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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