| Factors associated with intracranial hemorrhage in cases of cerebral arteriovenous malformation. | |
| | |
MedLine Citation:
|
PMID: 10690716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The standard categorization of arteriovenous malformations (AVMs) involves the Spetzler-Martin grading system, which uses a simple analysis of size, location (superficial or deep), and the presence of deep or superficial drainage. Hemodynamic risk factors are also thought to play important roles in the pathogenesis of these lesions and to be associated with the intracranial hemorrhage (ICH) rate. The actual hemodynamic factors for AVMs cannot be easily measured, but angioarchitectural features can be assessed and used as surrogate parameters. METHODS: The AVM angioarchitectural features for 662 patients were analyzed, and their associations with ICH as a presenting sign were studied. A cross-sectional analysis was used to qualify the strength of associations among clinical features, angioarchitectural characteristics, and ICH before treatment. RESULTS: The multivariate analysis indicated that arterial stenosis and arterial ectasia were associated with lower ICH rates, whereas venous stenosis increased the rate of ICH. The presence of angiogenesis modified the effects of arterial and venous stenosis. Furthermore, the effect of venous stenosis depended on the location of the nidus. The presented data do not support a direct positive association between associated aneurysms and ICH. CONCLUSION: Certain angiographic features seem to have prognostic potential with respect to the occurrence of ICH among patients with AVMs. A discriminatory prognostic index is proposed; its relevance must be proven in a future prospective study. |
| | |
Authors:
|
U Mansmann; J Meisel; M Brock; G Rodesch; H Alvarez; P Lasjaunias |
Related Documents
:
|
2300876 - A case of medullary venous malformations with an arterial component coexisting with art... 6646386 - Bilateral parietal arteriovenous malformations: report of a case. 997776 - Congenital carotid to jugular arteriovenous fistulae. 9202276 - Cerebral abscess as an unusual complication of coil embolization in a dural arterioveno... 12877606 - How to exclude the dilated false lumen in patients after a type b aortic dissection? th... 3823426 - Splanchnic artery aneurysms and pseudoaneurysms: transcatheter embolization. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Neurosurgery Volume: 46 ISSN: 0148-396X ISO Abbreviation: Neurosurgery Publication Date: 2000 Feb |
Date Detail:
|
Created Date: 2000-03-23 Completed Date: 2000-03-23 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7802914 Medline TA: Neurosurgery Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 272-9; discussion 279-81 Citation Subset: IM |
Affiliation:
|
Department of Medical Statistics, Epidemiology, and Informatics, Klinikum Benjamin Franklin, Free University Berlin, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Brain / blood supply Brain Ischemia / diagnosis, surgery Cerebral Angiography Cerebral Hemorrhage / diagnosis*, surgery Child Child, Preschool Cross-Sectional Studies Female Hemodynamics / physiology Humans Infant Intracranial Arteriovenous Malformations / diagnosis*, surgery Male Middle Aged Multivariate Analysis Neovascularization, Pathologic / diagnosis, surgery Prognosis Risk Factors Vascular Resistance / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Microsurgical resection of brainstem, thalamic, and basal ganglia angiographically occult vascular m...
Next Document: Ischemic events associated with unruptured intracranial aneurysms: multicenter clinical study and re...