Document Detail

Factors associated with clinically significant perinatal asphyxia in the Malaysian neonates: a case-control study.
MedLine Citation:
PMID:  1844086     Owner:  NLM     Status:  MEDLINE    
A 2-month prospective study was carried out in a Kuala Lumpur maternity hospital to determine the antenatal and intrapartum factors associated with perinatal asphyxia in the Malaysian neonates. The incidence of perinatal asphyxia was 18.7 per 1000 livebirths. Of the 75 asphyxiated neonates born during this period, 70 (93.3 per cent) were of term or post-term gestation. The incidence of perinatal asphyxia was more common in the neonates with one of the following characteristics: low birth weight (< 2500 g), breech delivery, or delivery by instrumentation or lower segment Caesarean section (P < 0.001). Conditional logistic regression analysis of the asphyxiated and the control neonates in a nested case-control study (after controlling for sex, race, birth weight, modes of delivery, and maternal gravida) showed that there were two associated factors which were of statistical significance. These were: small-for-gestation neonates and the presence of intrapartum problems. Our study suggests that to reduce the incidence of perinatal asphyxia, the common causes of small-for-gestation neonates and the common types of intrapartum problems should be identified to enable appropriate preventive measures to be carried out.
N Y Boo; M S Lye
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  38     ISSN:  0142-6338     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-04-02     Completed Date:  1993-04-02     Revised Date:  2008-09-12    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  284-9     Citation Subset:  IM    
Department of Pediatrics, Faculty of Medicine, National University of Malaysia, Jalan Raja Muda, Kuala Lumpur.
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MeSH Terms
Asphyxia Neonatorum / epidemiology*
Birth Weight
Case-Control Studies
Delivery, Obstetric / methods
Infant, Newborn
Infant, Small for Gestational Age
Malaysia / epidemiology
Pregnancy Complications
Prospective Studies
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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