| Factors affecting radioactive microsphere measurement of blood flow in pregnant guinea pigs. | |
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MedLine Citation:
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PMID: 3773466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Comparative blood flow studies were performed in pregnant guinea pigs using radioactive microspheres to test the effects of different sphere sizes on blood flow measurements and the relationship between flows obtained intraoperatively and those performed after 5 days of recovery from anesthesia and surgery. We observed that 1.5% of the cardiac output was shunted through the microcirculation of the carcass, gut, skin and endomyometrium when 15 mu microspheres were used. Intraoperative measurements of heart rate, cardiac output and placental blood flow are significantly lower than measurements made after 5 days recovery. These reductions were ameliorated with the addition of a continuous infusion of isoproterenol and the deletion of atropine from the anesthetic. |
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Authors:
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S Myers; J W Sparks; E L Makowski |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Laboratory animal science Volume: 36 ISSN: 0023-6764 ISO Abbreviation: Lab. Anim. Sci. Publication Date: 1986 Oct |
Date Detail:
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Created Date: 1986-12-12 Completed Date: 1986-12-12 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 1266503 Medline TA: Lab Anim Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 522-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Circulation* Female Gadolinium* Guinea Pigs Isotopes Microspheres Pregnancy Pregnancy, Animal / physiology* Radioisotopes Scandium* Tin* |
| Grant Support | |
ID/Acronym/Agency:
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HD00781/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Isotopes; 0/Radioisotopes; 7440-20-2/Scandium; 7440-31-5/Tin; 7440-54-2/Gadolinium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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