Document Detail

Factors affecting the prognosis of Ebstein's anomaly during fetal life.
MedLine Citation:
PMID:  9630115     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The echocardiographic criteria that have been used to evaluate severity of Ebstein's anomaly in utero are the same as those applied after birth. OBJECTIVE: The objective of this study was to establish prognostic criteria that take into account the peculiarities of the fetal hemodynamics. METHOD: The video recordings of eight fetuses with Ebstein's anomaly were retrospectively reviewed. RESULTS: The following indexes had no prognostic significance either on fetal or neonatal outcome: the ratio of functional tricuspid opening over the diameter of the annulus, the degree of displacement of the tricuspid valve opening, and the degree of tricuspid regurgitation. The index of severity (based on the surfaces of right atrium + atrialized right ventricle) and the cardiothoracic ratio had a significant impact only on neonatal survival. The smallest fossa ovalis were found in two fetuses who had hydrops. Fetuses who reached term without problems had higher left ventricular outputs. A positive linear correlation was found between the z score of the left ventricular output and the size of the fossa ovalis (r = 0.81, p < 0.05). CONCLUSION: The prognosis of Ebstein's anomaly during fetal life is not influenced by criteria described for postnatal life and may be related to factors that control the volume load of the left ventricle.
M Pavlova; J C Fouron; S P Drblik; N H van Doesburg; J L Bigras; J Smallhorn; J Harder; M Robertson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  135     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1998 Jun 
Date Detail:
Created Date:  1998-06-30     Completed Date:  1998-06-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1081-5     Citation Subset:  AIM; IM    
Department of Pediatrics, Sainte-Justine Hospital, University of Montreal, Quebec, Canada.
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MeSH Terms
Ebstein Anomaly / embryology*,  mortality
Fetal Death / etiology
Heart Atria / embryology
Infant, Newborn
Retrospective Studies
Tricuspid Valve / embryology
Tricuspid Valve Insufficiency / embryology
Ultrasonography, Prenatal
Ventricular Function, Left

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