| Factors affecting iron stores in infants 4-18 months of age. | |
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MedLine Citation:
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PMID: 11248874 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To determine the effects of dietary, physiological or environmental factors on body iron levels in infants aged 4-18 months. DESIGN: The daily iron intake of the infants was measured from a diet history obtained by interview using a standardised question sheet, previously validated against weighed intake (minimum 3 days) in an independent sample of 8 and 18 month old infants. Capillary blood samples were analyzed for haemoglobin, mean cell volume, haematocrit, zinc protoporphyrin and plasma ferritin concentration. Ferritin values were log-transformed prior to analysis to give a better approximation to the normal distribution and forward stepwise multiple linear regression was carried out using SPSS. SETTING: The city of Norwich, UK and some of its suburbs. SUBJECTS: One hundred and eighty-one healthy infants in age groups 4, 8, 12 and 18 months. RESULTS: Main determinants of iron stores in the 4 month old infants were birth weight (+ve (P < 0.001)) and body weight (-ve (P < 0.005)). In the 8 month old infants intake of cow's milk (-ve (P < 0.05)), belonging to a smoking household (-ve (P < 0.05)) and quantity of commercial babyfood consumed (+ve (P < 0.05)) were significant. In this age group there was a gender effect (girls > boys (P < 0.01)) and the gender effect remained at 12 months (girls > boys (P < 0.05)), but at 18 months only non-haem iron intake was a significant factor (-ve (P < 0.05)). CONCLUSIONS: At 4 months of age birth weight and body weight exert the greatest influence on iron stores, whereas by 8 months components of the weaning diet have an effect (commercial babyfood (+ve), cow's milk (-ve)); there is also a gender effect (girls > boys), possibly reflecting the different growth rate between boys and girls. At 12 and 18 months the only significant factors are gender (girls > boys) and non-haem iron intake (-ve) respectively. |
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Authors:
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S G Wharf; T E Fox; S J Fairweather-Tait; J D Cook |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of clinical nutrition Volume: 51 ISSN: 0954-3007 ISO Abbreviation: Eur J Clin Nutr Publication Date: 1997 Aug |
Date Detail:
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Created Date: 2001-03-15 Completed Date: 2001-06-21 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8804070 Medline TA: Eur J Clin Nutr Country: England |
Other Details:
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Languages: eng Pagination: 504-9 Citation Subset: IM |
Affiliation:
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Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, Norfolk, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Animals Birth Weight Body Weight England Environment Erythrocyte Indices Female Ferritins / blood* Hematocrit Hemoglobins / analysis, metabolism* Humans Infant Infant Food* Infant Nutritional Physiological Phenomena* Iron / analysis, blood* Iron, Dietary / administration & dosage* Male Milk / adverse effects Nutritional Status Questionnaires Regression Analysis Sex Factors |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobins; 0/Iron, Dietary; 7439-89-6/Iron; 9007-73-2/Ferritins |
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