Document Detail


Factors affecting the bioavailability of soy isoflavones in humans.
MedLine Citation:
PMID:  16915862     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To fully evaluate the potential risks and benefits of isoflavones to human health, an understanding of the physiological behavior of these compounds following ingestion is required. Numerous researchers have investigated the kinetics and extent of polyphenol absorption by measuring plasma concentrations and/or urinary excretion among adults after the ingestion of a single dose of polyphenol, provided as either a pure compound, plant extract, or whole food/beverage. Available data suggest isoflavones are more bioavailable than other flavonoid subclasses. This review will focus on our current understanding of factors affecting isoflavone absorption and metabolism in humans.
Authors:
Aedin Cassidy
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of AOAC International     Volume:  89     ISSN:  1060-3271     ISO Abbreviation:  J AOAC Int     Publication Date:    2006 Jul-Aug
Date Detail:
Created Date:  2006-08-18     Completed Date:  2006-11-08     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  9215446     Medline TA:  J AOAC Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1182-8     Citation Subset:  IM    
Affiliation:
University of East Anglia, School of Medicine, Norwich NR4 7TJ, United Kingdom. a.cassidy@uea.ac.uk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Absorption
Aging
Dose-Response Relationship, Drug
Doxorubicin / analogs & derivatives,  analysis
Female
Flavonoids / metabolism
Genistein / analysis
Glucosides / analysis
Growth Inhibitors / pharmacology
Humans
Isoflavones / analysis*,  metabolism,  pharmacokinetics*
Kinetics
Male
Phenols / metabolism
Soybeans / metabolism*
Chemical
Reg. No./Substance:
0/Flavonoids; 0/Glucosides; 0/Growth Inhibitors; 0/Isoflavones; 0/Phenols; 0/polyphenols; 116455-20-0/7-deoxy-13-dihydroadriamycinone; 23214-92-8/Doxorubicin; 446-72-0/Genistein; 486-66-8/daidzein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Assessing exposure to lignans and their metabolites in humans.
Next Document:  Mammary gland tumor promotion in F1 generation offspring from male and female rats exposed to soy is...