Document Detail

Factors affecting assisted reproductive technology (ART) pregnancy rates: a multivariate analysis.
MedLine Citation:
PMID:  16247715     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine factors instrumental in achieving a clinical pregnancy in assisted reproductive technology (ART) patients. METHODS: This study included 205 women undergoing their first ART cycle. Univariate and multivariate analyses were performed for patient demographics, in vitro production data, and factors associated with embryo transfer. Odds ratios (OR) were performed where appropriate. RESULTS: Our analyses indicated that age (OR: 0.879), specific year in which the cycle was performed (OR: 2.959), and use of intracytoplasmic sperm injection (OR: 2.867) altered potential pregnancy rate. In addition, percent fertilization (OR: 1.028), number of embryos transferred (OR: 1.842), type of catheter used to transfer the embryos (OR: 0.377), presence of blood on the catheter (OR .414), and embryologist (OR: 2.338) also altered pregnancy rate. CONCLUSIONS: Our data indicate patients' age, use of the Cook catheter, and presence of blood on the catheter reduce pregnancy rates. Performing ART in 1999, using ICSI, increasing fertilization rate, increasing number of embryos transferred (albeit less desirable when the chance of multiple gestation may occur), and transferring embryos via a particular embryologist, improve pregnancy rates.
Tiffany L Rhodes; Thomas P McCoy; H Lee Higdon; William R Boone
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  22     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-25     Completed Date:  2006-01-17     Revised Date:  2008-03-18    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  335-46     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Greenville Hospital System, South Carolina 29605, USA.
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MeSH Terms
Age Distribution
Birth Rate
Embryo Transfer
Multivariate Analysis
Pregnancy Outcome
Pregnancy Rate*
Reproductive Techniques, Assisted / statistics & numerical data*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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