Document Detail

Factors affecting the absorption of iron from cereals.
MedLine Citation:
PMID:  6317009     Owner:  NLM     Status:  MEDLINE    
Non-haem-iron absorption from a variety of cereal and fibre meals was measured in parous Indian women, using the erythrocyte utilization of radioactive Fe method. The present study was undertaken to establish whether alteration of the phytate and polyphenol contents of sorghum (Sorghum vulgare) affected Fe absorption from sorghum meals, and to assess the influence of fibre on Fe absorption. Removing the outer layers of sorghum grain by pearling reduced the polyphenol and phytate contents by 96 and 92% respectively. This treatment significantly increased the geometric mean Fe absorption from 0.017 to 0.035 (t 3.9, P less than 0.005). The geometric mean Fe absorption from a sorghum cultivar that lacked polyphenols (albino sorghum) was 0.043, which was significantly greater than the 0.019 absorbed from bird-proof sorghum, a cultivar with a high polyphenol content (t 2.83, P less than 0.05). Fe was less well absorbed from the phytate-rich pearlings of the albino sorghum than from the pearled albino sorghum (0.015 v. 0.035 (t 8.4, P less than 0.0005]. Addition of sodium phytate to a highly Fe-bioavailable broccoli (Brassica oleracea) meal reduced Fe absorption from 0.185 to 0.037. The geometric mean Fe absorption from malted sorghum porridge was 0.024 when 9.5 mg ascorbic acid were added and 0.094 when the ascorbic acid was increased to 50 mg (t 3.33, P less than 0.005). This enhancing effect of 50 mg ascorbic acid was significantly depressed to 0.04 by tea (t 38.1, P less than 0.0005).(ABSTRACT TRUNCATED AT 250 WORDS)
M Gillooly; T H Bothwell; R W Charlton; J D Torrance; W R Bezwoda; A P MacPhail; D P Derman; L Novelli; P Morrall; F Mayet
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of nutrition     Volume:  51     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-02-24     Completed Date:  1984-02-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  37-46     Citation Subset:  IM    
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MeSH Terms
Ascorbic Acid / pharmacology
Dietary Fiber / pharmacology*
Ferritins / blood
Hemoglobins / analysis
Intestinal Absorption* / drug effects
Iron / metabolism*
Phenols / pharmacology
Phytic Acid / pharmacology
Polymers / pharmacology
Species Specificity
Transferrin / analysis
Reg. No./Substance:
0/Flavonoids; 0/Hemoglobins; 0/Phenols; 0/Polymers; 0/polyphenols; 11096-37-0/Transferrin; 50-81-7/Ascorbic Acid; 7439-89-6/Iron; 83-86-3/Phytic Acid; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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