Document Detail

Factor X deficiency in the neonatal period.
MedLine Citation:
PMID:  7436479     Owner:  NLM     Status:  MEDLINE    
An infant with a severe deficiency of factor X presened in the neonatal period with uncontrollable bleeding from heel prick sites, spontaneous bruising, and haematoma. The deficiency was controlled by infusions of dried human factors II, IX, and X concentrate; the half-life of the infused factor X material is only 18 hours. Despite prophylactic weekly infusions of factor X concentrate, the child developed a fatal intracerebral haemorrhage when only 4 months old. Coagulation studies on both parents and the elder sister showed no obvious coagulation abnormality.
S J Machin; M R Winter; S C Davies; I J Mackie
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  55     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1980 May 
Date Detail:
Created Date:  1981-01-16     Completed Date:  1981-01-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  406-8     Citation Subset:  AIM; IM    
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MeSH Terms
Factor X Deficiency*
Infant, Newborn
Infant, Newborn, Diseases*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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