Document Detail

Factor VII deficiency with intracranial hemorrhage: a case report.
MedLine Citation:
PMID:  8252461     Owner:  NLM     Status:  MEDLINE    
Factor VII deficiency is an autosomal recessive hereditary disorder characterized by a normal partial thromboplastin time and a prolonged prothrombin time. Definite diagnosis of this condition requires a specific Factor VII assay. Its quite uncommon occurrence in the newborn was first described by Alexander and associates in 1951. A one-day-old male, full-term newborn was presented here with skin pallor, respiratory distress and bitemporal bulging masses noted immediately after birth. Computed tomography scan of the brain revealed a subgaleal hematoma and subarachnoid hemorrhage. Laboratory studies revealed prolonged prothrombin time and a Factor VII level less than 1%. Literature on the clinical manifestation and management of Factor VII deficiency is reviewed briefly.
S C Chen; T K Chang; C S Chi; S G Shu
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Zhonghua yi xue za zhi = Chinese medical journal; Free China ed     Volume:  52     ISSN:  0578-1337     ISO Abbreviation:  Zhonghua Yi Xue Za Zhi (Taipei)     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1994-01-10     Completed Date:  1994-01-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0005327     Medline TA:  Zhonghua Yi Xue Za Zhi (Taipei)     Country:  TAIWAN    
Other Details:
Languages:  eng     Pagination:  190-3     Citation Subset:  IM    
Department of Pediatric, Veterans General Hospital-Taichung, Taiwan, R.O.C.
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MeSH Terms
Cerebral Hemorrhage / etiology*,  radiography,  surgery
Factor VII / analysis
Factor VII Deficiency / complications*
Genetic Counseling
Infant, Newborn
Prothrombin Time
Reg. No./Substance:
9001-25-6/Factor VII

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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