Document Detail


Factor analysis of metabolic syndrome components in the Coronary Artery Risk Development in Young Adults (CARDIA) study: examination of factors by race-sex groups and across time.
MedLine Citation:
PMID:  20071194     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: This study tests hypotheses of one-, two-, three-, and four-factor models of metabolic syndrome (MetS) components and assesses the consistency and fit of the factor models 10 years later using confirmatory factor analysis in a large biracial sample of men and women.
METHODS: With the use of data from the baseline and year-10 exams of the Coronary Artery Risk Development in Young Adults Study, confirmatory factor analysis was performed overall and for race- and sex-specific groups for one-, two-, three-, and four-factor MetS models in 3403 white and black men and women at baseline and in 2532 white and black men and women 10 years later. Metabolic risk variables used in the factor analysis were insulin resistance (HOMA-IR), fasting glucose, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, systolic and diastolic blood pressure, waist circumference, waist-hip ratio, triceps skinfolds, and uric acid.
RESULTS: Three- and four-factor models of MetS achieved excellent fits of the data, ranging from 0.92 to 0.96 for race- and sex-specific models and from the baseline to year-10 exams.
CONCLUSIONS: The results suggest that MetS factors are consistent across time and race-sex groups. When investigating the MetS, it is necessary to evaluate race-sex groups.
Authors:
T Freeman Ferguson; Ellen Funkhouser; Jeffrey Roseman
Related Documents :
15779484 - Prevalence of metabolic syndrome in a large health check-up population in taiwan.
24668104 - Glycated hemoglobin measurement and prediction of cardiovascular disease.
17039474 - High-sensitivity c-reactive protein, adiposity, and blood pressure in the yakut of sibe...
18270234 - Significant associations of metabolic syndrome and its components with silent lacunar i...
17196714 - The prevalence of enduring postnatal perineal morbidity and its relationship to perinea...
10964834 - Angle-closure glaucoma in an urban population in southern india. the andhra pradesh eye...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2010-01-13
Journal Detail:
Title:  Annals of epidemiology     Volume:  20     ISSN:  1873-2585     ISO Abbreviation:  Ann Epidemiol     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-06-10     Revised Date:  2013-05-31    
Medline Journal Info:
Nlm Unique ID:  9100013     Medline TA:  Ann Epidemiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  194-200     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Community Health, Saint Louis University School of Public Health, St Louis, MO 63104-1314, USA. tfergus2@slu.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
African Americans / statistics & numerical data*
Blood Glucose / analysis
Body Mass Index
Cholesterol / blood
Coronary Disease / blood,  epidemiology*,  ethnology
European Continental Ancestry Group / statistics & numerical data*
Factor Analysis, Statistical
Female
Humans
Longitudinal Studies
Male
Metabolic Syndrome X / blood,  epidemiology*,  ethnology
Obesity / blood,  epidemiology,  ethnology
Risk Assessment
Triglycerides / blood
Uric Acid / blood
Young Adult
Grant Support
ID/Acronym/Agency:
N01 HC095095/HC/NHLBI NIH HHS; N01-HC-48047/HC/NHLBI NIH HHS; N01-HC-48048/HC/NHLBI NIH HHS; N01-HC-48049/HC/NHLBI NIH HHS; N01-HC-48050/HC/NHLBI NIH HHS; N01-HC-95095/HC/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Triglycerides; 57-88-5/Cholesterol; 69-93-2/Uric Acid
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Age- and gender-specific estimates of partnership formation and dissolution rates in the Seattle sex...
Next Document:  Adipokines and nutritional status for patients on maintenance hemodialysis.