| Factor analysis of metabolic syndrome components in the Coronary Artery Risk Development in Young Adults (CARDIA) study: examination of factors by race-sex groups and across time. | |
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MedLine Citation:
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PMID: 20071194 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: This study tests hypotheses of one-, two-, three-, and four-factor models of metabolic syndrome (MetS) components and assesses the consistency and fit of the factor models 10 years later using confirmatory factor analysis in a large biracial sample of men and women. METHODS: With the use of data from the baseline and year-10 exams of the Coronary Artery Risk Development in Young Adults Study, confirmatory factor analysis was performed overall and for race- and sex-specific groups for one-, two-, three-, and four-factor MetS models in 3403 white and black men and women at baseline and in 2532 white and black men and women 10 years later. Metabolic risk variables used in the factor analysis were insulin resistance (HOMA-IR), fasting glucose, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, systolic and diastolic blood pressure, waist circumference, waist-hip ratio, triceps skinfolds, and uric acid. RESULTS: Three- and four-factor models of MetS achieved excellent fits of the data, ranging from 0.92 to 0.96 for race- and sex-specific models and from the baseline to year-10 exams. CONCLUSIONS: The results suggest that MetS factors are consistent across time and race-sex groups. When investigating the MetS, it is necessary to evaluate race-sex groups. |
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Authors:
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T Freeman Ferguson; Ellen Funkhouser; Jeffrey Roseman |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2010-01-13 |
Journal Detail:
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Title: Annals of epidemiology Volume: 20 ISSN: 1873-2585 ISO Abbreviation: Ann Epidemiol Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-17 Completed Date: 2010-06-10 Revised Date: 2013-05-31 |
Medline Journal Info:
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Nlm Unique ID: 9100013 Medline TA: Ann Epidemiol Country: United States |
Other Details:
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Languages: eng Pagination: 194-200 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Community Health, Saint Louis University School of Public Health, St Louis, MO 63104-1314, USA. tfergus2@slu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult African Americans / statistics & numerical data* Blood Glucose / analysis Body Mass Index Cholesterol / blood Coronary Disease / blood, epidemiology*, ethnology European Continental Ancestry Group / statistics & numerical data* Factor Analysis, Statistical Female Humans Longitudinal Studies Male Metabolic Syndrome X / blood, epidemiology*, ethnology Obesity / blood, epidemiology, ethnology Risk Assessment Triglycerides / blood Uric Acid / blood Young Adult |
| Grant Support | |
ID/Acronym/Agency:
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N01 HC095095/HC/NHLBI NIH HHS; N01-HC-48047/HC/NHLBI NIH HHS; N01-HC-48048/HC/NHLBI NIH HHS; N01-HC-48049/HC/NHLBI NIH HHS; N01-HC-48050/HC/NHLBI NIH HHS; N01-HC-95095/HC/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose; 0/Triglycerides; 57-88-5/Cholesterol; 69-93-2/Uric Acid |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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